Pricing
Choose the best option for you
For Individuals
Hobby
- 50 credits for premium LLM models (one-time) (1 credit per tool use in agent mode)
- 10 Protein AI model simulation credits one time (Boltz-1, RFDiffusion & RFAntibody, more coming soon)
- Includes PyMOL(TM)
Basic
- Everything in Hobby
- 300 credits for premium LLM models per month (1 credit per tool use in agent mode)
- 50 Protein AI model simulation credits per month (Boltz-1, RFDiffusion & RFAntibody, more coming soon)
Pro
- Everything in Basic
- 500 credits for premium LLM models per month (1 credit per tool use in agent mode)
- 100 Protein AI model simulation credits per month (Boltz-1, RFDiffusion & RFAntibody, more coming soon)
For Companies
Enterprise
- Large scale access to compute for Protein AI Models
- Multi user
- Dedicated support and setup
Frequently Asked Questions
Why isn't Nano Helix completely free?
Running advanced AI models require significant resources. To sustain Nano Helix without compromising its performance and innovation, we need to cover operational costs.
Where are my projects stored?
All sessions are stored locally, so only you have access to your projects.
Who owns the outputs generated by Nano Helix?
You do! All outputs and generated content are owned by you, whether you're using the free or premium version of Nano Helix. You are free to use them for any purpose, including commercial applications.
How can I cancel or update my credit card?
You can go to your account settings in nanohelix.ai and update your credit card information or cancel your subscription.
Can I cancel my subscription anytime?
Yes! You can cancel anytime by logging into nanohelix.ai --> Settings --> Manage subscription.
Can I get a refund?
Unfortunately, we cannot offer refunds as costs incurred for running AI models are high. In turn, our upstream providers do not let us ask for refunds. You can cancel anytime though and your subscription ends.
Which protein AI models are currently supported?
We currently support two cutting-edge protein AI models: Boltz (open-source implementation of AlphaFold3), RFDiffusion, RFAntibody and ProteinMPNN. We're actively working on integrating more models to provide you with a comprehensive suite of protein design and analysis tools.
Does Nano Helix include AlphaFold 3 for protein structure prediction?
Nano Helix ships with Boltz, an open-source implementation of AlphaFold 3, so you can run accurate protein structure prediction in complex with ligands, RNA or DNA right away—no extra downloads required.
Is Nano Helix free protein modeling software or do I need a paid plan?
The Hobby plan is free forever and lets you model proteins with AlphaFold-based Boltz and access limited AI design credits. Paid plans unlock higher monthly credits, advanced pipelines, and priority compute.
Can I run Nano Helix's protein simulation software on macOS, Windows, and Linux?
Nano Helix offers native installers for macOS and Windows
Can Nano Helix design de-novo proteins or only predict structures?
Both. Use RFDiffusion and ProteinMPNN for de-novo or guided protein sequence design, then evaluate confidence scores and structural metrics in one place.
How do I integrate Nano Helix with PyMOL for 3D visualization?
Nano Helix ships with a built-in PyMOL™ engine. Every model you generate opens instantly in an embedded PyMOL viewer—no manual export steps needed.
Can I build automated protein modeling pipelines without coding?
Yes. The Pipeline feature lets you chain steps— RFDiffusion design → ProteinMPNN design → Boltz (AlphaFold) design → RMSD filter—using a drag-and-drop UI.
Does Nano Helix support antibody design like RF Antibody?
Yes. RF Antibody is included with an interactive UI, with automatic pairing to ProteinMPNN and AlphaFold for structure refinement.
How does Nano Helix compare to ColabFold or ChimeraX?
Unlike cloud notebooks, Nano Helix offers a desktop app with a simple UI to run models. In addition, it allows you to automate protein modeling workflows, and unifies prediction, design, and visualization. It also offers an AI Copilot that automates tasks and guide you through simulations.
Can Nano Helix predict protein–ligand, DNA, or RNA complexes?
Yes. Boltz supports complex-mode prediction, allowing you to model protein–ligand, protein–DNA, or protein–RNA interactions out-of-the-box.
Can I customize RFDiffusion symmetry settings in Nano Helix?
Yes. Advanced settings let you specify point-group symmetry, guiding potentials, and design constraints without editing config files manually.
Where can I ask more questions?
Feel free to reach out directly for support. We're here to help you make the most out of Nano Helix!